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mRNA is a versatile drug class which can be designed and optimized pharmacologically and immunologically, making it suitable for a broad range of applications such as prophylactic and therapeutic vaccines or protein substitutes. Its full potential may be harnessed when used in combination with other drug classes. BioNTech is working to provide effective treatments for different diseases, which is why we are leveraging four key drug classes – mRNA, cell therapies, small molecules, and antibodies – to enhance the immune system’s therapeutic potential. This presentation explores the synergistic benefits of mRNA in combination with other drug classes and explores the application of mRNA technology when combined with CAR T cell therapy for the treatment of specific oncology indications.