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Environmental Sustainability in Single-use Materials

Jun 29, 2022 3:45pm ‐ Jun 29, 2022 4:00pm

Credits: None available.


Biopharmaceutical manufacturing provides products of significant value in human health. Nevertheless, facility designers, suppliers, and entity sponsors are working to reduce its environmental footprint. New methods are reducing the environmental burden generated by single-use (SU) materials. Science-based approaches include environmental LCAs of the entire value chain, emerging environmental burden reduction technologies, and the digitally assisted rational design of solutions. Specific manufacturing solutions can be organized into the seven Rs: Rethink , Reduce, Reengineer, Reuse, Recycle, Recover, and Reduce. Rethinking includes if SU is appropriate for a specific operation, or reviewing the facility distance to SU materials supply or recycling vendors. An example of reduction is the shorting of a seed train, thereby eliminating some SU materials. Reengineering packaging to use recyclable materials, or less plastic, is popular. Reusing SU materials in-house has been accomplished, e.g., employing a sterile fluid material container to collect intermediate product. There are new approaches to recycling, including those supporting more circular economies. Recovering energy through advanced incineration is popular, and reduction of discard from exceeding expiry dates in inventory is alleviated through advanced supply chain methods. Finally, the employment of building information modeling (BIM) systems aids in developing life cycle-based project designs and asset selection.



Credits: None available.

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