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AI has been identified as a key science-technological field with high impact in Pharma 4.0, but how much real is this implementation in biopharma today? AI is being used to maximize the value proposal in other industries (e.g. retail, fintec). How can Pharma bring a differential value to patients? AI is being used today as a tool for applying scientific knowledge in complex problems, understanding the continuously changing reality from a multivariable perspective. This view is fully aligned with the Quality goals and the capabilities boosted by AI in areas like predictability, recommendations, human language processing or classification are bringing value to the classic Quality Control, building an holistic approach towards the Total Quality fully patient-centric oriented.