To secure product supply many different control strategies are implemented. However, these are rarely connected so a change to one control strategy may impact another control strategy in an unforeseen way. The Holistic Control Strategy connects the different CS elements across the entire supply chain to secure a robust end-to-end manufacturing process delivering speedy, reliable, consistent quality products throughout the entire product lifetime. The implementation of the HCS requires different capabilities related to digital, analytical, process, quality, and organisational maturity. This presentation will define and discuss the role of the Holistic Control Strategy and the capabilities required for successful implementation.