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Share with attendants experiences from Respimat project start to product transfer and ramp-up. The facility is for a combination product based on a cartridge (aseptic liquid filling) and a soft mist inhalator. Describe in this presentation the experience of a project set-up such as project organization with tandems of experts, unique project plan, importance of design freeze, ...) How to do knowledge management along the project to ensure a successful start-up (from project to routine organization) by sharing experiences such as international assignments for project members, include external expertise from the network and other companies, etc. How to balance cost vs quality standards?